A major review conducted by a world expert in patient safety and aimed at introducing a "zero-harm culture" in the NHS is set to be published later.
Professor Don Berwick, a former adviser to US President Barack Obama, was asked by David Cameron earlier this year to conduct a safety review of English hospitals.
He believes the scandal at Mid Staffordshire NHS Foundation Trust, where hundreds of patients died unnecessarily, should act as a catalyst to drive improvements in the health service.
The review is expected to recommend minimum staffing levels for hospitals and suggest a legal duty for staff to admit their mistakes.
Professor Berwick has said he believes the NHS could offer the safest healthcare in the world.
As part of the review, a team of experts from the UK and US examined why some patients needlessly suffer or die in hospital because of errors.
One basic element of creating a zero-harm culture includes using checklists before surgery and asking patients to give their name before any treatment is given.
Hundreds of patients were routinely neglected at Stafford Hospital Health Secretary Jeremy Hunt told Sky News the report would make clear imposing targets from the centre can be counter-productive.
He also insisted it was not his role to decide how many nurses and doctors worked at individual hospitals, insisting this should be left to those in the front line.
"We have had a top down NHS where ministers have decided and tried to mandate things at the centre and that hasn't worked," he said.
In March, Professor Berwick said he would recommend how the NHS could take "serious and profound" action to improve safety.
He said: "Assuring patient safety and high quality care is never automatic. It requires the constant attention of leaders and continual support to the workforce.
"I have read, and been deeply affected by, the harrowing personal stories of individuals and families who were so badly injured when this commitment flagged at Mid Staffordshire Hospitals.
"Our group will do whatever it can to recommend how the NHS in England take serious and profound action, learning from this tragedy to make patient care and treatment as safe as it can possibly be, and ever safer.
"Indeed, there is no reason why English healthcare cannot aspire to be and become the safest healthcare in the world."
Mid Staffordshire was at the centre of a public inquiry into Stafford Hospital, where hundreds of patients were routinely neglected.
Led by Robert Francis QC, the inquiry reported earlier this yea and highlighted the "appalling and unnecessary suffering of hundreds of people".
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